Searchable abstracts of presentations at key conferences in endocrinology

ea0022p808 | Thyroid | ECE2010

Thyroid hormones regulate the production of complement mannan-binding lectin regardless of the MBL2 genotype: a cohort study of 95 patients with autoimmune thyroid disorders.

Potlukova Eliska , Jiskra Jan , Freiberger Tomas , Limanova Zdenka , Zivorova Dana , Malickova Karin , Springer Drahomira , Grodecka Lucie , Antosova Marie , Telicka Zdenek , Pesickova Sattu Sinikka , Trendelenburg Marten

Introduction: Complement mannan-binding lectin (MBL) deficiency is associated with increased susceptibility to infections and autoimmune diseases. Previous studies suggested that the production of MBL is stimulated by thyroid hormones. The aim of our study was to investigate this association in patients with autoimmune thyroid diseases (AITD).Methods: Serum levels of MBL and parameters of the thyroid function were determined in 62 patients with Hashimoto...